Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893669 | 1.00 | CNR2 (0.35) | CNR2CNR1FCER2MMP9CA1 | |
| SCHEMBL10204084 | 1.00 | CNR2 (0.35) | CNR2CNR1FCER2MMP9CA1 | |
| SCHEMBL4682544 | 0.83 | CA2 (0.49) | CA1CA2CA7 | |
| SCHEMBL10114274 | 0.83 | CA2 (0.49) | CA1CA2CA7 | |
| SCHEMBL30807639 | 0.83 | CA2 (0.49) | CA1CA2CA7 | |
| SCHEMBL20469133 | 0.81 | GAA (0.36) | — | |
| SCHEMBL7765993 | 0.80 | ALOX15 (0.40) | CNR2CNR1FCER2MMP9 | |
| SCHEMBL20468937 | 0.80 | GAA (0.33) | — | |
| SCHEMBL6418 | 0.80 | CA2 (0.40) | CNR2CA1CA2CA7 | |
| SCHEMBL3265337 | 0.80 | ALDH1A1 (0.33) | CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE BAHAMAS LTD (BS) | 2017-03-22 | — | — | EP | disclosed |
| WO-2010144869-A2 | PROTEASE INHIBITORS | NEKTAR THERAPEUTICS (US) | 2010-12-16 | — | — | WO | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |