SCHEMBL776598

SCHEMBL776598

Cc1ccc(-c2cc(C)cc(-c3ccccc3)c2C(=O)P(=O)(O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC7 Q8WUI4 1/20 0.48
PTPN5 P54829 1/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42
HPRT1 P00492 1/20 0.41
NPC1 O15118 3/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
POLB P06746 2/20 0.38
LMNA P02545 2/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778487 0.79 CNR2 (0.41) HDAC7MAPTL3MBTL1LMNAMAPK1
SCHEMBL779661 0.79 HDAC7 (0.44) HDAC7PTGDR2CYP3A4CYP2C9L3MBTL1
SCHEMBL3887561 0.79 HDAC7 (0.47) HDAC7PTPN5PTGDR2HPRT1NPC1
Phosphoric Acid SCHEMBL9637834 0.76 PTPN5 (0.47) HDAC7PTPN5HPRT1NPC1RAB9A
SCHEMBL778488 0.76 AKR1C3 (0.41) HDAC7NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL779346 0.75 GRM2 (0.39) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL776599 0.71 HDAC7 (0.40) HDAC7PTPN5NPC1RAB9ASMN1; SMN2
SCHEMBL11418617 0.71 LMNA (0.43) HDAC7PTPN5LMNAHPGD
SCHEMBL28693316 0.70 MAPK8 (0.39) NPC1RAB9ASMN1; SMN2MAPTLMNA
Bicarbonate SCHEMBL27683080 0.69 SMN1; SMN2 (0.56) HPRT1NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed