SCHEMBL778488

SCHEMBL778488

Cc1ccc(C(=O)c2c(-c3ccccc3)ccc(C)c2C(=O)P(=O)(O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.41
CNR2 P34972 1/20 0.40
ALDH1A1 P00352 4/20 0.40
LMNA P02545 3/20 0.40
TDP1 Q9NUW8 2/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SRD5A2 P31213 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
NPSR1 Q6W5P4 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
POLB P06746 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779417 0.85 HPGD (0.39) ALDH1A1LMNAL3MBTL1MAPTHPGD
SCHEMBL778487 0.82 CNR2 (0.41) AKR1C3CNR2ALDH1A1LMNATDP1
SCHEMBL776598 0.76 HDAC7 (0.48) ALDH1A1LMNATDP1MAPK1L3MBTL1
SCHEMBL779856 0.75 ALDH1A1 (0.48) AKR1C3ALDH1A1LMNATDP1L3MBTL1
SCHEMBL777792 0.75 LMNA (0.44) AKR1C3CNR2ALDH1A1LMNATDP1
SCHEMBL27717943 0.71 GRM6 (0.47) CNR2ALDH1A1LMNATDP1MAPK1
SCHEMBL779661 0.71 HDAC7 (0.44) ALDH1A1LMNAL3MBTL1HPGDHDAC7
SCHEMBL6911946 0.71 AKR1C3 (0.60) AKR1C3CNR2ALDH1A1LMNATDP1
SCHEMBL17748183 0.70 ALDH1A1 (0.47) CNR2ALDH1A1LMNATDP1L3MBTL1
SCHEMBL6692576 0.69 ESR2 (0.46) ALDH1A1TDP1L3MBTL1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed