SCHEMBL776599

SCHEMBL776599

Cc1ccc(-c2c(C)ccc(C(=O)P(=O)(O)O)c2-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC7 Q8WUI4 1/20 0.40
FABP4 P15090 1/20 0.38
PTPN5 P54829 1/20 0.38
ALDH1A1 P00352 4/20 0.38
TP53 P04637 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 5/20 0.37
HTT P42858 2/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887564 0.78 PTPN5 (0.40) FABP4PTPN5ALDH1A1TP53LMNA
SCHEMBL779662 0.75 FABP4 (0.39) FABP4ALDH1A1SMN1; SMN2HPGDKMT2A
SCHEMBL776598 0.71 HDAC7 (0.48) HDAC7PTPN5ALDH1A1LMNASMN1; SMN2
SCHEMBL3895681 0.70 LMNA (0.41) PTPN5ALDH1A1LMNASMN1; SMN2POLB
SCHEMBL3885257 0.70 S1PR3 (0.39) HDAC7PTPN5LMNASMN1; SMN2MAPT
SCHEMBL779347 0.70 MYC (0.38) ALDH1A1HTTMAPTNPC1RAB9A
SCHEMBL22391489 0.70 MAPT (0.48) FABP4ALDH1A1LMNASMN1; SMN2HTT
SCHEMBL2784914 0.69 AKR1C3 (0.61) ALDH1A1LMNASMN1; SMN2HTTMAPT
SCHEMBL17292709 0.69 KIF11 (0.47) ALDH1A1LMNASMN1; SMN2MAPTNPC1
SCHEMBL3883335 0.68 LMNA (0.42) PTPN5ALDH1A1LMNASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed