Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | STAT5B | P51692 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771116 | 0.87 | LTB4R2 (0.42) | PTPN1LTB4R2FFAR1AKR1B1OXTR | |
| SCHEMBL4939408 | 0.79 | LTB4R2 (0.41) | PTPN1LTB4R2FFAR1AKR1B1OXTR | |
| SCHEMBL9243744 | 0.78 | ESR2 (0.37) | LTB4R2FFAR1AKR1B1OXTRAVPR1A | |
| SCHEMBL9243751 | 0.75 | BDKRB1 (0.46) | LTB4R2FFAR1AKR1B1AGTR1BRS3 | |
| SCHEMBL9587078 | 0.73 | FNTA (0.37) | LTB4R2STAT5BFNTAFNTB | |
| SCHEMBL27488491 | 0.71 | ALDH1A1 (0.36) | PTPN1LTB4R2 | |
| SCHEMBL8875659 | 0.71 | LTB4R2 (0.42) | LTB4R2FFAR1AKR1B1OXTRAVPR1A | |
| SCHEMBL21065276 | 0.70 | AGTR1 (0.34) | LTB4R2AGTR1STAT5B | |
| SCHEMBL9586916 | 0.70 | FNTA (0.36) | LTB4R2STAT5BFNTAFNTB | |
| SCHEMBL8874537 | 0.70 | NR1H4 (0.42) | FFAR1AKR1B1OXTRAVPR1AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881212-B1 | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-31 | — | — | EP | claimed |
| US-6177587-B1 | INTERMEDIATES FOR THE PRODUCTION OF MEDICINES; REACTING A MIXTURE CONTAINING A MONO-HALOGENO COMPOUND OR A DI-HALOGENO COMPOUND WITH AN AMIDO NITROBENZENE DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-23 | — | — | US | disclosed |