Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978960 | 0.93 | CTSS (0.44) | L3MBTL1CTSLCTSSCTSKCYP1A2 | |
| SCHEMBL7765281 | 0.89 | L3MBTL1 (0.38) | L3MBTL1CTSLCTSSCTSKCYP1A2 | |
| SCHEMBL703724 | 0.86 | L3MBTL1 (0.39) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL19240522 | 0.85 | CTSL (0.47) | L3MBTL1CTSLCTSSCTSKCYP1A2 | |
| SCHEMBL28379504 | 0.81 | L3MBTL1 (0.36) | L3MBTL1CTSLCTSSCTSKCYP1A2 | |
| SCHEMBL28374086 | 0.81 | FFAR4 (0.38) | L3MBTL1CTSLCTSSCTSKCYP1A2 | |
| SCHEMBL12238352 | 0.81 | TYR (0.42) | L3MBTL1CTSLCTSSCTSKCYP1A2 | |
| SCHEMBL10383011 | 0.80 | L3MBTL1 (0.46) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL11953512 | 0.80 | L3MBTL1 (0.39) | L3MBTL1CTSLCTSSCTSKCYP1A2 | |
| SCHEMBL17527769 | 0.79 | L3MBTL1 (0.48) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |