Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766243 | 1.00 | MAPT (0.41) | MAPTRAB9AL3MBTL1ITGB3ITGA2B | |
| SCHEMBL7766234 | 1.00 | MAPT (0.41) | MAPTRAB9AL3MBTL1ITGB3ITGA2B | |
| SCHEMBL7762668 | 0.93 | RAB9A (0.38) | MAPTRAB9AL3MBTL1ITGB3ITGA2B | |
| SCHEMBL7762671 | 0.93 | RAB9A (0.38) | MAPTRAB9AL3MBTL1ITGB3ITGA2B | |
| SCHEMBL7762662 | 0.93 | RAB9A (0.38) | MAPTRAB9AL3MBTL1ITGB3ITGA2B | |
| SCHEMBL7769856 | 0.87 | ITGB3 (0.38) | ITGB3ITGA2BALDH1A1LMNACYP3A4 | |
| SCHEMBL7769853 | 0.87 | ITGB3 (0.38) | ITGB3ITGA2BALDH1A1LMNACYP3A4 | |
| SCHEMBL7769850 | 0.87 | ITGB3 (0.38) | ITGB3ITGA2BALDH1A1LMNACYP3A4 | |
| SCHEMBL7762581 | 0.87 | FAAH (0.35) | ITGB3ITGA2BALDH1A1HRH3DDB1 | |
| SCHEMBL7762577 | 0.87 | FAAH (0.35) | ITGB3ITGA2BALDH1A1HRH3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |