SCHEMBL7766545

SCHEMBL7766545

CCCCCCC(C)C(CC)(CCCC)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.43
GPR84 Q9NQS5 8/20 0.43
FFAR1 O14842 2/20 0.43
CA1 P00915 2/20 0.42
MAPT P10636 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
CA2 P00918 1/20 0.41
HSPD1 P10809 1/20 0.41
BLM P54132 1/20 0.41
HSPE1 P61604 1/20 0.41
FFAR4 Q5NUL3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28774057 0.87 ACE2 (0.43) ACE2GPR84FFAR1CA1MAPT
SCHEMBL15412278 0.84 GPR84 (0.44) ACE2GPR84FFAR1MAPTLCK
SCHEMBL9331686 0.84 GPR84 (0.44) ACE2GPR84FFAR1MAPTLCK
SCHEMBL29150446 0.84 CA2 (0.39) ACE2GPR84FFAR1CA1MAPT
SCHEMBL11336656 0.83 CA2 (0.42) ACE2GPR84FFAR1CA1MAPT
SCHEMBL27998480 0.83 FFAR4 (0.53) GPR84FFAR1MAPTPPARDFFAR4
SCHEMBL2346085 0.83 ACE2 (0.40) ACE2GPR84FFAR1CA1MAPT
SCHEMBL2904335 0.83 FDPS (0.46) ACE2GPR84FFAR1MAPTLCK
SCHEMBL28527998 0.82 ACE2 (0.42) ACE2GPR84FFAR1MAPTLCK
SCHEMBL27998386 0.82 FFAR4 (0.56) GPR84FFAR1MAPTPPARDBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0817621-B1 PHARMACEUTICAL COMPOSITION FOR TRANSDERMIC DELIVERY SANOFI SYNTHELABO (FR) 2001-06-20 EP claimed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES CBR1, CYP2A13, CBR3 ACE2 3762/4885GPR84 722/4885FFAR1 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.