Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447563 | 0.90 | NAMPT (0.55) | NAMPTROCK2NPC1KDM4EHTR2C | |
| SCHEMBL7770409 | 0.86 | CHRM3 (0.51) | NAMPTSIGMAR1CHRM3 | |
| SCHEMBL6027850 | 0.81 | PRSS1 (0.50) | NAMPTNPC1KDM4ESIGMAR1 | |
| SCHEMBL29313543 | 0.80 | CHRM3 (0.56) | KDM4ECHRM3PKM | |
| SCHEMBL7769975 | 0.80 | ALDH1A1 (0.56) | GLSROCK2NPC1BRD4CREBBP | |
| SCHEMBL7770471 | 0.77 | BRD4 (0.48) | GLSROCK2NPC1BRD4CREBBP | |
| SCHEMBL13981921 | 0.77 | GLS (0.55) | NAMPTGLSBRD4CREBBP | |
| SCHEMBL16181822 | 0.77 | GLS (0.55) | NAMPTGLSBRD4CREBBP | |
| SCHEMBL1165088 | 0.77 | GLS (0.55) | NAMPTGLSBRD4CREBBP | |
| SCHEMBL30069429 | 0.77 | GLS (0.55) | NAMPTGLSBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115731-A2 | NOVEL PYRANOSES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000014097-A2 | NOVEL PYRANOSES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-03-16 | — | — | WO | disclosed |