SCHEMBL7769975

SCHEMBL7769975

CC(C)(C)OC(=O)NCc1cccc(CNC(=O)C2CCNCC2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
BRD4 O60885 1/20 0.48
CREBBP Q92793 1/20 0.48
GLS O94925 3/20 0.47
USP2 O75604 1/20 0.46
HPGD P15428 1/20 0.46
EPHX2 P34913 1/20 0.46
HTR2C P28335 1/20 0.46
PKM P14618 3/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
ROCK2 O75116 2/20 0.44
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MC4R P32245 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774001 0.86 PKM (0.51) ALDH1A1GLSPKMLMNACYP3A4
SCHEMBL7770471 0.85 BRD4 (0.48) SMN1; SMN2BRD4CREBBPGLSHPGD
SCHEMBL7773978 0.85 GLS (0.45) ALDH1A1BRD4CREBBPGLSUSP2
SCHEMBL7773979 0.85 GLS (0.45) ALDH1A1BRD4CREBBPGLSUSP2
SCHEMBL301842 0.85 BRD4 (0.47) ALDH1A1SMN1; SMN2BRD4CREBBPGLS
Hydrochloric Acid SCHEMBL2034724 0.84 BRD4 (0.46) ALDH1A1SMN1; SMN2BRD4CREBBPGLS
SCHEMBL2584476 0.82 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2USP2HPGDEPHX2
Acetic Acid SCHEMBL973925 0.82 BRD4 (0.45) ALDH1A1SMN1; SMN2BRD4CREBBPGLS
SCHEMBL28801811 0.82 BRD4 (0.47) ALDH1A1SMN1; SMN2BRD4CREBBPGLS
SCHEMBL7771603 0.81 ROCK2 (0.53) BRD4CREBBPCHRM3ROCK2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115731-A2 NOVEL PYRANOSES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 2001-07-18 EP disclosed
WO-2000014097-A2 NOVEL PYRANOSES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-03-16 WO disclosed