SCHEMBL776669

SCHEMBL776669

O=S(=O)(Oc1ccccc1F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 7/20 0.40
DRD3 P35462 5/20 0.40
DRD4 P21917 3/20 0.40
DRD1 P21728 1/20 0.40
DRD5 P21918 1/20 0.40
CXCL8 P10145 1/20 0.39
ELANE P08246 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
HTR1D P28221 2/20 0.36
HTR5A P47898 1/20 0.36
EPAS1 Q99814 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27669021 0.98 DRD2 (0.39) DRD2DRD3DRD4DRD1DRD5
Biphenyl SCHEMBL4360975 0.93 ADORA2A (0.38) DRD2DRD3DRD4DRD1DRD5
SCHEMBL1712875 0.87 DRD2 (0.43) DRD2DRD3DRD4DRD1DRD5
SCHEMBL776975 0.85 SLC6A2 (0.39) DRD2DRD3DRD4DRD1DRD5
SCHEMBL30919460 0.85 SLC6A2 (0.39) DRD2DRD3DRD4DRD1DRD5
SCHEMBL7023211 0.82 DRD2 (0.42) DRD2DRD3DRD4DRD1DRD5
SCHEMBL779828 0.81 EPAS1 (0.50) DRD2DRD3DRD4DRD1DRD5
SCHEMBL31305332 0.81 EPAS1 (0.50) DRD2DRD3DRD4DRD1DRD5
SCHEMBL25323447 0.80 FABP1 (0.39) DRD2DRD3DRD4DRD1DRD5
SCHEMBL13580797 0.80 DRD2 (0.36) DRD2DRD3DRD4DRD1DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12440581-B2 Fluorophores for super-resolution imaging HOWARD HUGHES MEDICAL INSTITUTE (US) 2025-10-14 US disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
CN-113692401-A Process for producing aromatic amino acid derivative 中外制药株式会社 2021-11-23 CN disclosed
CN-113614085-A Inhibitors of influenza virus replication and uses thereof 广东东阳光药业有限公司 2021-11-05 CN disclosed
US-20210085805-A1 FLUOROPHORES FOR SUPER-RESOLUTION IMAGING HOWARD HUGHES MEDICAL INSTITUTE 2021-03-25 US disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
US-20190229372-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-25 US disclosed
US-10333172-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-25 US disclosed
WO-2014196930-A1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-12-11 WO disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
WO-2011121350-A1 4 -AMINO -7,8- DIHYDROPYRIMIDO [5, 4 - F] [1, 4] OXAZEPIN- 5 ( 6H) - ONE BASED DGAT1 INHIBITORS ASTRAZENECA AB (SE) 2011-10-06 WO disclosed
CN-1854133-B Heterocycle-bearing onium salts WAKO PURE CHEM IND LTD 2010-11-10 CN disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed
CN-100475803-C Heterocyclic onium salt WAKO PURE CHEM IND LTD (JP) 2009-04-08 CN disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
CN-1854133-A Heterocycle-bearing onium salts WAKO PURE CHEM IND LTD (JP) 2006-11-01 CN disclosed
CN-1622943-A Heterocyclic onium salt WAKO PURE CHEM IND LTD (JP) 2005-06-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210085805-A1 FLUOROPHORES FOR SUPER-RESOLUTION IMAGING CHAT, FABP7, CD68 DRD2 751/4885DRD3 1278/4885DRD4 952/4885
US-12440581-B2 Fluorophores for super-resolution imaging CHAT, FABP7, CD68 DRD2 751/4885DRD3 1278/4885DRD4 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.