SCHEMBL7023211

SCHEMBL7023211

O=S(=O)(Oc1ccccc1-c1ccccc1OS(=O)(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 9/20 0.42
DRD3 P35462 6/20 0.41
DRD4 P21917 4/20 0.41
DRD1 P21728 2/20 0.41
DRD5 P21918 2/20 0.41
GPR3 P46089 1/20 0.40
SLC22A12 Q96S37 1/20 0.39
ELANE P08246 1/20 0.38
HTR1D P28221 2/20 0.37
HSD11B1 P28845 1/20 0.36
HTR5A P47898 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16926997 0.98 DRD2 (0.41) DRD2DRD3DRD4DRD1DRD5
SCHEMBL28166225 0.91 PTGS2 (0.41) DRD2DRD3DRD4DRD1DRD5
SCHEMBL367003 0.90 DRD2 (0.42) DRD2DRD3DRD4DRD1DRD5
Iodide SCHEMBL8735171 0.89 SLC22A12 (0.49) DRD2DRD3DRD4DRD1DRD5
SCHEMBL14075537 0.89 ALDH1A1 (0.50) DRD2DRD3DRD4DRD1DRD5
SCHEMBL1712875 0.89 DRD2 (0.43) DRD2DRD3DRD4DRD1DRD5
SCHEMBL12646496 0.88 DRD2 (0.37) DRD2DRD3DRD4DRD1DRD5
SCHEMBL18015659 0.86 DRD2 (0.43) DRD2DRD3DRD4DRD1DRD5
Iodide SCHEMBL8736611 0.85 DRD2 (0.38) DRD2DRD3DRD4DRD1DRD5
SCHEMBL28014198 0.85 DRD2 (0.40) DRD2DRD3DRD4DRD1DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11174211-B2 Aryl compounds and polymers and methods of making and using the same NEVADA RESEARCH & INNOVATION CORPORATION (US) 2021-11-16 US disclosed
EP-3271346-B1 ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME UNIV NEVADA RENO (US) 2021-05-05 EP disclosed
US-10941168-B2 Phosphepine matrix compound for a semiconducting material NOVALED GMBH (DE) 2021-03-09 US disclosed
US-20200331831-A1 ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2020-10-22 US disclosed
US-10550056-B2 Aryl compounds and polymers and methods of making and using the same BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2020-02-04 US disclosed
US-20190202848-A1 Phosphepine Matrix Compound for a Semiconducting Material NOVALED GMBH (DE) 2019-07-04 US disclosed
US-20180244596-A1 ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA (US) 2018-08-30 US disclosed
US-20180182960-A1 Organic Light Emitting Device Comprising Polar Matrix and Metal Dopant NOVALED GMBH (DE) 2018-06-28 US disclosed
US-20180182960-A1 Organic Light Emitting Device Comprising Polar Matrix and Metal Dopant NOVALED GMBH (DE) 2018-06-28 US disclosed
US-20180162890-A1 Phosphepine Matrix Compound for a Semiconducting Material NOVALED GMBH (DE) 2018-06-14 US disclosed
WO-2016149633-A1 ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2016-09-22 WO disclosed
EP-0684249-B1 Phosphine compounds, complexes containing the phosphine compounds as ligands, and process for producing optically active aldehydes using the phosphine compounds or complexes TAKASAGO PERFUMERY CO LTD (JP) 2003-02-19 EP disclosed
JP-2003040867-A DICARBAZOLE DERIVATIVE BOUND BY CHIRAL ARYLENE, AND METHOD FOR PRODUCING THE SAME JAPAN SCIENCE & TECHNOLOGY CORP 2003-02-13 JP disclosed
EP-0684230-B1 4- (R)-1'-formylethyl azetidin-2-one derivatives TAKASAGO PERFUMERY CO LTD (JP) 2002-07-03 EP disclosed
EP-0614903-B1 Process for producing optically active aldehydes using transition metal-phosphine complexes, and process for producing intermediates for carbapenem antibiotics using the same complexes TAKASAGO PERFUMERY CO LTD (JP) 2000-09-20 EP disclosed
US-5530150-A HAVING PHOSPHINE AND PHOSPHITE GROUPS IN SAME MOLECULE; CATALYST SELECTIVITY TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-06-25 US disclosed
EP-0684249-A1 Phosphine compounds, complexes containing the phosphine compounds as ligands, and process for producing optically active aldehydes using the phosphine compounds or complexes Takasago International Corporation (JP) 1995-11-29 EP disclosed
EP-0684230-A1 4- (R)-1'-formylethyl azetidin-2-one derivatives Takasago International Corporation (JP) 1995-11-29 EP disclosed
EP-0614903-A2 Phosphine compounds, complexes containing the phosphine compounds as ligands, process for producing optically active aldehydes using the phosphine compounds, or complexes, and 4-[(R)-1' formylethyl]azetidin-2-one derivatives Takasago International Corporation (JP) 1994-09-14 EP disclosed
US-5241044-A Soluble poly(p-phenylene)s EDISON POLYMER INNOVATION CORPORATION (US) 1993-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941168-B2 Phosphepine matrix compound for a semiconducting material PHOSPHO1, PSPH, PNMT DRD2 2792/4885DRD3 3552/4885DRD4 2820/4885
US-20200331831-A1 ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME AHR, TYR, PAH DRD2 620/4885DRD3 675/4885DRD4 283/4885
US-20190202848-A1 Phosphepine Matrix Compound for a Semiconducting Material PHOSPHO1, PSPH, PNMT DRD2 2792/4885DRD3 3552/4885DRD4 2820/4885
US-20180244596-A1 ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME AHR, TYR, PAH DRD2 620/4885DRD3 675/4885DRD4 283/4885
US-11174211-B2 Aryl compounds and polymers and methods of making and using the same AHR, TYR, PAH DRD2 620/4885DRD3 675/4885DRD4 283/4885
US-20180162890-A1 Phosphepine Matrix Compound for a Semiconducting Material HRH3, HRH4, HRH1 DRD2 156/4885DRD3 935/4885DRD4 389/4885
US-10550056-B2 Aryl compounds and polymers and methods of making and using the same AHR, TYR, PAH DRD2 620/4885DRD3 675/4885DRD4 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.