SCHEMBL7766770

SCHEMBL7766770

OC(c1ccccc1)(c1ccc(C(F)(F)F)cc1)C(O)(c1ccccc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.70
TSHR P16473 1/20 0.70
KIF11 P52732 3/20 0.58
CYP19A1 P11511 1/20 0.55
TRPV6 Q9H1D0 2/20 0.54
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ACP3 P15309 1/20 0.46
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
MGLL Q99685 1/20 0.44
BACE1 P56817 1/20 0.44
SRD5A2 P31213 1/20 0.43
PTPN1 P18031 1/20 0.43
CYP1A1 P04798 1/20 0.43
MAOB P27338 1/20 0.43
CYP1B1 Q16678 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30915210 1.00 ALDH1A1 (0.70) ALDH1A1TSHRKIF11CYP19A1TRPV6
SCHEMBL12264154 0.85 CYP19A1 (0.71) ALDH1A1TSHRKIF11CYP19A1TRPV6
SCHEMBL7768289 0.84 TSHR (0.54) ALDH1A1TSHRKIF11CYP19A1RAB9A
Trifluoromethylbenzene SCHEMBL8692 0.84 TSHR (1.00) ALDH1A1TSHRKIF11CYP19A1TRPV6
Trifluoromethylbenzene SCHEMBL27760126 0.84 TSHR (1.00) ALDH1A1TSHRKIF11CYP19A1TRPV6
Trifluoromethylbenzene SCHEMBL175647 0.84 TSHR (1.00) ALDH1A1TSHRKIF11CYP19A1TRPV6
SCHEMBL7173455 0.84 CYP1A2 (0.48) ALDH1A1TSHRPTPN1CYP3A4CYP2D6
SCHEMBL36629 0.84 CYP1A2 (0.48) ALDH1A1TSHRPTPN1CYP3A4CYP2D6
Trifluoromethylbenzene SCHEMBL28851750 0.81 TSHR (0.82) ALDH1A1TSHRKIF11CYP19A1TRPV6
Trifluoromethylbenzene SCHEMBL1549721 0.81 TSHR (0.82) ALDH1A1TSHRKIF11CYP19A1TRPV6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0800116-B1 Photoresist composition MITSUBISHI CHEM CORP (JP) 2001-08-22 EP disclosed
US-5759736-A Photoresist composition MITSUBISHI CHEMICAL CORPORATION (JP) 1998-06-02 US disclosed
EP-0800116-A1 Photoresist composition Mitsubishi Chemical Corporation (JP) 1997-10-08 EP disclosed
US-4081278-A AND A REDUCIBLE DYE OR DYE PRECURSOR EASTMAN KODAK COMPANY (US) 1978-03-28 US disclosed