Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10583894 | 0.93 | TSHR (0.56) | TSHRHPGDTDP1NAAAHCAR2 | |
| SCHEMBL8946360 | 0.86 | TDP1 (0.63) | TSHRHPGDTDP1ATMNAAA | |
| SCHEMBL7771219 | 0.84 | TSHR (0.57) | TSHRHPGDTDP1ATMNAAA | |
| SCHEMBL3889780 | 0.84 | ATM (0.47) | TSHRHPGDTDP1ATMNAAA | |
| SCHEMBL7772502 | 0.83 | TSHR (0.60) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL21275447 | 0.82 | ALDH1A1 (0.56) | TSHRHPGDTDP1ATMNAAA | |
| SCHEMBL352761 | 0.81 | TSHR (0.47) | TSHRHPGDTDP1ATMNAAA | |
| SCHEMBL1471358 | 0.81 | TDP1 (0.51) | TSHRHPGDTDP1ALDH1A1NPSR1 | |
| SCHEMBL7241147 | 0.81 | TDP1 (0.45) | TSHRHPGDTDP1NAAAALDH1A1 | |
| SCHEMBL7235503 | 0.81 | TDP1 (0.45) | TSHRHPGDTDP1NAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504469-B2 | having an XY block structure, block X being composed of a polyester and block Y of a polysiloxane, and having an end group which is free from reactive groups exhibit a drastically increased activity in respect of lubricity, scratch resistance and water repellency | BYK-CHEMIE GMBH (DE) | 2009-03-17 | — | — | US | disclosed |
| EP-0711813-B1 | Antifouling coating composition | HITACHI CHEMICAL CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-5773508-A | BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0711813-A2 | Coating varnish composition and antifouling coating composition | Hitachi Chemical Co., Ltd. (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0301401-A2 | Leukotriene antagonists, process for their preparation, their use in the treatment of illnesses | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-01 | — | — | EP | disclosed |