Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756076 | 0.89 | TDP1 (0.54) | TDP1GAAMGAMSIMGAM2 | |
| SCHEMBL8611277 | 0.85 | TDP1 (0.41) | TDP1GAAMGAMSIMGAM2 | |
| SCHEMBL5873282 | 0.85 | TDP1 (0.61) | TDP1GAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8670951 | 0.83 | TDP1 (0.61) | TDP1GAAMGAMSIMGAM2 | |
| SCHEMBL8063306 | 0.83 | TDP1 (0.59) | TDP1GAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11357983 | 0.82 | TDP1 (0.59) | TDP1GAAMGAMSIMGAM2 | |
| SCHEMBL7767124 | 0.81 | TSHR (0.52) | TDP1TSHRALDH1A1HSD17B10NPSR1 | |
| SCHEMBL6319093 | 0.81 | GAA (0.46) | TDP1GAAMGAMSIMGAM2 | |
| SCHEMBL7774752 | 0.80 | TSHR (0.49) | TDP1GAAMGAMSIMGAM2 | |
| SCHEMBL5781501 | 0.80 | TDP1 (0.49) | TDP1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540162-B2 | Preparation of functional homocysteine residues in polypeptides and peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-02-03 | — | — | US | disclosed |
| US-20240092833-A1 | PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-03-21 | — | — | US | disclosed |
| US-11732008-B2 | Preparation of functional homocysteine residues in polypeptides and peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-22 | — | — | US | disclosed |
| US-20190119322-A1 | PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2017189860-A1 | PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-02 | — | — | WO | disclosed |
| EP-1699843-B1 | PROCESSES FOR PREPARING PRINTABLE AND PRINTED ARTICLES | DU PONT (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-1697143-B1 | PRINT RECEPTIVE ARTICLES | DU PONT (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20110070192-A1 | Method of preparation of novel nucleoside analogs and uses | AUSPEX PHARMACEUTICALS, INC. | 2011-03-24 | — | — | US | disclosed |
| US-20110070192-A1 | Method of preparation of novel nucleoside analogs and uses | AUSPEX PHARMACEUTICALS, INC. | 2011-03-24 | — | — | US | disclosed |
| US-20110070192-A1 | Method of preparation of novel nucleoside analogs and uses | AUSPEX PHARMACEUTICALS, INC. | 2011-03-24 | — | — | US | disclosed |
| US-6632518-B1 | Primer layer of an amine functional acrylic polymer, thermoplastic adhesive layer containing acid modified polyolefin, thermoplastic substrate | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-10-14 | — | — | US | disclosed |
| US-6626530-B2 | Fluoropolymer protective coatings | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-09-30 | — | — | US | disclosed |
| EP-1330366-A2 | PROCESS FOR MAKING PROTECTED PRINTED IMAGES | E.I. DUPONT DE NEMOURS AND COMPANY, Legal Patent Records Center (US) | 2003-07-30 | — | — | EP | disclosed |
| US-20020150734-A1 | Process for making protected printed images | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-10-17 | — | — | US | disclosed |
| WO-2002038385-A2 | PROCESS FOR MAKING PROTECTED PRINTED IMAGES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-05-16 | — | — | WO | disclosed |
| EP-1131375-A1 | FLUOROPOLYMER FILM STRUCTURES AND LAMINATES PRODUCED THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-12 | — | — | EP | disclosed |
| EP-0711813-B1 | Antifouling coating composition | HITACHI CHEMICAL CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000022032-A1 | FLUOROPOLYMER FILM STRUCTURES AND LAMINATES PRODUCED THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-04-20 | — | — | WO | disclosed |
| US-5773508-A | BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0711813-A2 | Coating varnish composition and antifouling coating composition | Hitachi Chemical Co., Ltd. (JP) | 1996-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119322-A1 | PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES | BHMT2, BHMT, PTMS | TDP1 1843/4885GAA 4463/4885MGAM 2559/4885 |
| US-20110070192-A1 | Method of preparation of novel nucleoside analogs and uses | RNGTT, TYMP, SLC29A1 | TDP1 629/4885GAA 293/4885MGAM 948/4885 |
| US-12540162-B2 | Preparation of functional homocysteine residues in polypeptides and peptides | PTMS, AHCY, BHMT2 | TDP1 1427/4885GAA 4733/4885MGAM 2834/4885 |
| US-11732008-B2 | Preparation of functional homocysteine residues in polypeptides and peptides | BHMT2, BHMT, PTMS | TDP1 1843/4885GAA 4463/4885MGAM 2559/4885 |
| US-20240092833-A1 | PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES | BHMT2, BHMT, PTMS | TDP1 1843/4885GAA 4463/4885MGAM 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.