Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310648 | 0.74 | TAS1R3 (0.37) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL310647 | 0.74 | TAS1R3 (0.37) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL16951918 | 0.72 | TSHR (0.48) | ALDH1A1TAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL11418791 | 0.71 | TSHR (0.63) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL1554601 | 0.69 | GPR35 (0.42) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL1554603 | 0.69 | GPR35 (0.42) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL7548898 | 0.69 | TSHR (0.50) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL6503152 | 0.69 | MAPT (0.50) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL6503149 | 0.69 | MAPT (0.50) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL6503145 | 0.69 | MAPT (0.50) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879230-B1 | OPTICALLY ACTIVE PHENYL PYRIMIDINE DERIVATIVE AS ANALGESIC AGENT | GLAXO GROUP LTD (GB) | 2001-07-25 | — | — | EP | disclosed |