Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769357 | 0.89 | ALDH1A1 (0.37) | KMT2APOLBMEN1HTTALDH1A1 | |
| SCHEMBL9033045 | 0.85 | POLB (0.37) | KMT2APOLBMEN1HTTALDH1A1 | |
| SCHEMBL7767486 | 0.85 | POLB (0.37) | KMT2APOLBMEN1HTTALDH1A1 | |
| SCHEMBL20968646 | 0.68 | POLB (0.51) | KMT2APOLBMEN1HTTALDH1A1 | |
| SCHEMBL14973545 | 0.67 | KMT2A (0.60) | KMT2AMEN1HTTALDH1A1HPGD | |
| SCHEMBL3657694 | 0.65 | HTT (0.59) | KMT2AMEN1HTTALDH1A1HPGD | |
| SCHEMBL9450597 | 0.65 | KMT2A (0.55) | KMT2AMEN1HTTALDH1A1HPGD | |
| SCHEMBL7767464 | 0.65 | TP53 (0.32) | KMT2AKDM4E | |
| SCHEMBL9450633 | 0.64 | HTT (0.58) | KMT2AMEN1HTTALDH1A1HPGD | |
| SCHEMBL3658650 | 0.64 | HTT (0.62) | KMT2AMEN1HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |