Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767455 | 0.89 | KMT2A (0.36) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL7767486 | 0.82 | POLB (0.37) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL9033654 | 0.82 | POLB (0.37) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL9033045 | 0.82 | POLB (0.37) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL14973545 | 0.72 | KMT2A (0.60) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL9450597 | 0.70 | KMT2A (0.55) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL19222914 | 0.70 | KMT2A (0.35) | KMT2AMEN1HTTSMN1; SMN2KDM4E | |
| SCHEMBL9450600 | 0.70 | KMT2A (0.55) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL3657694 | 0.70 | HTT (0.59) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL14994325 | 0.70 | KMT2A (0.51) | ALDH1A1HPGDKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |