Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762197 | 0.86 | ACHE (0.45) | SIGMAR1 | |
| SCHEMBL7766819 | 0.83 | MEN1 (0.36) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL7764943 | 0.78 | MEN1 (0.42) | — | |
| SCHEMBL7765650 | 0.76 | MEN1 (0.45) | SIGMAR1 | |
| SCHEMBL7767457 | 0.71 | EHMT2 (0.38) | — | |
| SCHEMBL7765797 | 0.70 | KMT2A (0.38) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL7769361 | 0.68 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL7767441 | 0.68 | MEN1 (0.35) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL7766761 | 0.66 | CYP3A4 (0.40) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL7769344 | 0.65 | MEN1 (0.36) | CYP1A2CYP3A4CYP2D6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |