Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766819 | 0.85 | MEN1 (0.36) | KMT2AMEN1EHMT2HSD17B2ALDH1A1 | |
| SCHEMBL7764943 | 0.81 | MEN1 (0.42) | KMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL7765650 | 0.78 | MEN1 (0.45) | KMT2AMEN1ALDH1A1HSD17B10HCRTR1 | |
| SCHEMBL7767457 | 0.78 | EHMT2 (0.38) | KMT2AMEN1EHMT2ALDH1A1HSD17B10 | |
| SCHEMBL7769361 | 0.76 | CYP1A2 (0.40) | KMT2AMEN1EHMT2HSD17B2ALDH1A1 | |
| SCHEMBL7769377 | 0.74 | CRBN (0.39) | KMT2AMEN1EHMT2ALDH1A1HSD17B10 | |
| SCHEMBL7764980 | 0.73 | CYP3A4 (0.35) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL7761783 | 0.72 | LMNA (0.46) | KMT2AMEN1EHMT2ALDH1A1 | |
| SCHEMBL7765809 | 0.71 | EHMT2 (0.42) | KMT2AMEN1EHMT2ALDH1A1GAA | |
| SCHEMBL7767456 | 0.70 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2D6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |