Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766819 | 0.87 | MEN1 (0.36) | EHMT2MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL7764943 | 0.82 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL7765650 | 0.80 | MEN1 (0.45) | MEN1KMT2AALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL7765797 | 0.78 | KMT2A (0.38) | EHMT2MEN1KMT2AALDH1A1HCRTR1 | |
| SCHEMBL7761783 | 0.76 | LMNA (0.46) | EHMT2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7769361 | 0.73 | CYP1A2 (0.40) | EHMT2MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL7767456 | 0.71 | CYP1A2 (0.36) | — | |
| SCHEMBL7767441 | 0.70 | MEN1 (0.35) | EHMT2MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL7765772 | 0.70 | SDCBP (0.38) | EHMT2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7765809 | 0.69 | EHMT2 (0.42) | EHMT2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |