Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767882 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1POLBMAPK1RCE1 | |
| SCHEMBL7771929 | 0.83 | SCN5A (0.40) | KDM4EALDH1A1POLBMAPK1RCE1 | |
| SCHEMBL7767875 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1POLBMAPK1RCE1 | |
| SCHEMBL7772054 | 0.79 | FPR1 (0.41) | KDM4EALDH1A1POLBMAPK1RCE1 | |
| SCHEMBL7767873 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1POLBMAPK1RCE1 | |
| SCHEMBL7773814 | 0.76 | PTGDR2 (0.45) | KDM4EALDH1A1MAPK1RCE1TP53 | |
| SCHEMBL7377097 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1MAPK1RCE1TSHR | |
| SCHEMBL8117512 | 0.70 | SCN5A (0.42) | — | |
| SCHEMBL7771932 | 0.70 | F2 (0.42) | KDM4EALDH1A1POLBHSD17B10HPGD | |
| SCHEMBL7771927 | 0.68 | KDM4E (0.44) | KDM4EALDH1A1POLBMAPK1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |