Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775650 | 0.88 | KDM4E (0.48) | KDM4ESMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL7771929 | 0.86 | SCN5A (0.40) | KDM4ESMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7767896 | 0.85 | KDM4E (0.47) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7772054 | 0.82 | FPR1 (0.41) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7773814 | 0.78 | PTGDR2 (0.45) | KDM4EALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL7773573 | 0.77 | KAT2B (0.44) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7377097 | 0.75 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1FPR1LMNA | |
| SCHEMBL8117512 | 0.73 | SCN5A (0.42) | F2PRSS1 | |
| SCHEMBL7771932 | 0.72 | F2 (0.42) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7771637 | 0.71 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2ALDH1A1FPR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |