Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124061 | 0.87 | FPR1 (0.41) | FPR1FPR2IDH1KDM4EALDH1A1 | |
| SCHEMBL7775650 | 0.84 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL7772064 | 0.83 | FPR1 (0.39) | FPR1FPR2IDH1KDM4ESMN1; SMN2 | |
| SCHEMBL7767882 | 0.82 | KDM4E (0.40) | FPR1FPR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7771929 | 0.80 | SCN5A (0.40) | KDM4ESMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL7767896 | 0.79 | KDM4E (0.47) | IDH1KDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7773577 | 0.78 | KAT2B (0.47) | FPR1FPR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7773814 | 0.72 | PTGDR2 (0.45) | KDM4EALDH1A1RAB9AMAPK1RCE1 | |
| SCHEMBL7377097 | 0.71 | KDM4E (0.44) | FPR1FPR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7771932 | 0.70 | F2 (0.42) | KDM4ESMN1; SMN2ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |