Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608404 | 0.80 | RIPK1 (0.41) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL68538 | 0.80 | RIPK1 (0.45) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL8127525 | 0.78 | RIPK1 (0.44) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL11543845 | 0.78 | RIPK1 (0.48) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL17854020 | 0.77 | RIPK1 (0.47) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL20306752 | 0.77 | RIPK1 (0.45) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL8553662 | 0.76 | ALDH1A1 (0.44) | SLC6A4AOC3 | |
| SCHEMBL13957168 | 0.76 | RIPK1 (0.39) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL14431333 | 0.74 | TAAR1 (0.50) | RIPK1HRH1SLC6A3CACNA1FCHRM2 | |
| SCHEMBL416895 | 0.74 | TAAR1 (0.50) | RIPK1HRH1SLC6A3CACNA1FCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105112-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009108-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |