Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12766982 | 0.78 | MAPK1 (0.52) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL10139336 | 0.78 | MAPK1 (0.52) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL10139335 | 0.78 | MAPK1 (0.52) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL7767977 | 0.76 | RIPK1 (0.44) | SLC6A4AOC3 | |
| SCHEMBL6814333 | 0.72 | MAPK1 (0.50) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL9330212 | 0.72 | CA1 (0.48) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL3481587 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL1219105 | 0.70 | CA12 (0.50) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL18609431 | 0.69 | NPSR1 (0.46) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL6023939 | 0.69 | CA1 (0.55) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786378-A | FKBP TYPE IMMUNOPHILLINS FOR NERVOUS SYSTEM DISORDERS | GPI NIL HOLDINGS, INC. (US) | 1998-07-28 | — | — | US | disclosed |