SCHEMBL7768002

SCHEMBL7768002

CCOC([SiH3])(OCC)c1ccccc1CCCCBr

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
LIPG Q9Y5X9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611887 0.80 SIRT2 (0.30)
SCHEMBL28883883 0.75 TDP1 (0.38) CYP4F2CYP4A11LIPG
SCHEMBL17861582 0.72 HDAC1 (0.50) LIPG
SCHEMBL22540607 0.71 LIPG (0.46) CYP4F2CYP4A11LIPG
Bromide SCHEMBL29026100 0.70 LIPG (0.34) LIPG
SCHEMBL9670333 0.70 TDP1 (0.42) CYP4F2CYP4A11LIPG
SCHEMBL28820101 0.70 TSHR (0.35)
SCHEMBL8070890 0.69 L3MBTL1 (0.51)
SCHEMBL8077715 0.69 CYP4F2 (0.45) CYP4F2CYP4A11LIPG
SCHEMBL8072142 0.69 LIPG (0.50) CYP4F2CYP4A11LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705838-B1 Process for the preparation of silane polysulfides CROMPTON CORP (US) 2001-05-23 EP disclosed
US-5596116-A Process for the preparation of silane polysulfides OSI SPECIALTIES, INC. (US) 1997-01-21 US disclosed
EP-0705838-A2 Process for the preparation of silane polysulfides OSi SPECIALTIES, INC. (US) 1996-04-10 EP disclosed
US-5489701-A REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION OSI SPECIALTIES, INC. (US) 1996-02-06 US disclosed
US-5466848-A Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane OSI SPECIALTIES, INC. (US) 1995-11-14 US disclosed
US-4129585-A NO FORMATION OF HYDROGEN SULFIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-12-12 US disclosed