Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818992 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL13450447 | 0.78 | GABRA1 (0.36) | TSHRACHEGABRA1GABRB2NLRP3 | |
| SCHEMBL9507129 | 0.78 | GABRA1 (0.36) | TSHRACHEGABRA1GABRB2NLRP3 | |
| SCHEMBL1069637 | 0.77 | ALDH1A1 (0.46) | GAA | |
| SCHEMBL8101437 | 0.76 | TSHR (0.35) | TSHRACHEGABRA1GABRB2NLRP3 | |
| SCHEMBL28092974 | 0.76 | TSHR (0.35) | TSHRACHEGABRA1GABRB2NLRP3 | |
| SCHEMBL14163871 | 0.76 | TSHR (0.35) | TSHRACHEGABRA1GABRB2NLRP3 | |
| SCHEMBL25838476 | 0.73 | TSHR (0.32) | TSHRACHENLRP3 | |
| SCHEMBL7629997 | 0.72 | KCNN4 (0.40) | — | |
| SCHEMBL10481874 | 0.71 | TSHR (0.39) | TSHRGABRA1GABRB2NLRP3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102898456-B | O-benzyldiethoxymethylsilane and preparation method thereof | UNIV HANGZHOU NORMAL | 2015-06-17 | — | — | CN | disclosed |