Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764135 | 0.84 | MAOB (0.36) | MAPTALDH1A1PTPN1HPGDMAOB | |
| SCHEMBL7772085 | 0.84 | KDM4E (0.34) | NPC1RAB9AMAPTPOLBALDH1A1 | |
| SCHEMBL8044974 | 0.80 | S1PR1 (0.40) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL7688081 | 0.78 | LSS (0.62) | PTPN1LSS | |
| SCHEMBL7688083 | 0.78 | LSS (0.62) | PTPN1LSS | |
| SCHEMBL9360246 | 0.78 | LSS (0.46) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7767737 | 0.77 | ADRB2 (0.38) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL8035630 | 0.77 | LSS (0.60) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL8045307 | 0.77 | LSS (0.46) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL8049755 | 0.77 | LSS (0.46) | NPC1RAB9AMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |