Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769135 | 0.90 | PTGES (0.36) | KDM4EALDH1A1PTPN1 | |
| SCHEMBL7768082 | 0.84 | NPC1 (0.38) | KDM4EALDH1A1PTPN1POLBMAPT | |
| SCHEMBL7764172 | 0.83 | KDM4E (0.33) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL7764135 | 0.81 | MAOB (0.36) | ALDH1A1PTPN1MAPTLMNA | |
| SCHEMBL7681554 | 0.81 | LSS (0.46) | KDM4EPTPN1MAPTLMNA | |
| SCHEMBL7681546 | 0.81 | LSS (0.46) | KDM4EPTPN1MAPTLMNA | |
| SCHEMBL7772100 | 0.80 | KDM4E (0.33) | KDM4EPTPN1POLBBTKEGFR | |
| SCHEMBL7769445 | 0.80 | KDM4E (0.36) | KDM4EPOLBBRD4 | |
| SCHEMBL8047273 | 0.79 | IL2 (0.35) | KDM4EALDH1A1BRD4 | |
| Fumaric Acid SCHEMBL7681356 | 0.79 | LSS (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |