Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769445 | 0.85 | KDM4E (0.36) | ADRB2ADRB1ADRB3POLBKDM4E | |
| SCHEMBL7768123 | 0.85 | KDM4E (0.37) | ADRB3LSSKDM4EOPRK1MEN1 | |
| SCHEMBL8044974 | 0.84 | S1PR1 (0.40) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL8047494 | 0.80 | ALDH1A1 (0.43) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL7679251 | 0.79 | LSS (0.60) | ADRB2ADRB1ADRB3LSSKDM4E | |
| SCHEMBL7767798 | 0.79 | LSS (0.60) | ADRB2ADRB1ADRB3LSSKDM4E | |
| SCHEMBL7679255 | 0.79 | LSS (0.60) | ADRB2ADRB1ADRB3LSSKDM4E | |
| SCHEMBL7679262 | 0.79 | LSS (0.60) | ADRB2ADRB1ADRB3LSSKDM4E | |
| SCHEMBL7768082 | 0.77 | NPC1 (0.38) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL7768105 | 0.77 | PTGES (0.34) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |