Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768094 | 0.86 | LSS (0.53) | ALDH1A1LSSKMT2ALMNA | |
| SCHEMBL5045831 | 0.85 | LSS (0.52) | ALDH1A1LSSKMT2ALMNA | |
| SCHEMBL27499031 | 0.81 | LSS (0.39) | ALDH1A1MAPTLSSUTS2RGAA | |
| SCHEMBL7687746 | 0.80 | LSS (0.62) | LSSKMT2A | |
| Hydrochloric Acid SCHEMBL7687496 | 0.79 | LSS (0.61) | LSSKMT2A | |
| SCHEMBL27596279 | 0.78 | LSS (0.40) | LSSUTS2RKDM4ELMNA | |
| SCHEMBL27596324 | 0.78 | LSS (0.40) | LSSUTS2RKDM4ELMNA | |
| SCHEMBL7208349 | 0.78 | LSS (0.40) | LSSUTS2RKDM4ELMNA | |
| SCHEMBL27596322 | 0.78 | LSS (0.40) | LSSUTS2RKDM4ELMNA | |
| SCHEMBL27578407 | 0.77 | LSS (0.39) | ALDH1A1LSSUTS2RKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |