SCHEMBL7768142

SCHEMBL7768142

C=C(CC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.38
TET3 O43151 1/20 0.38
TET1 Q8NFU7 1/20 0.38
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
GRM1 Q13255 1/20 0.37
GRM2 Q14416 1/20 0.37
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6061456 1.00 TET2 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL14125809 0.93 TET2 (0.41) TET2TET3TET1GRIK1GRIK2
SCHEMBL10938859 0.89 TET2 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL2180876 0.85 TET2 (0.43) TET2TET3TET1GRIK1GRIK2
SCHEMBL30979237 0.81 THRB (0.41) THRB
SCHEMBL1594710 0.76 TET2 (0.43) TET2TET3TET1THRB
SCHEMBL5165627 0.76 TET2 (0.43) TET2TET3TET1THRB
SCHEMBL1815910 0.76 TET2 (0.36) TET2TET3TET1GRIK1GRIK2
SCHEMBL1553292 0.72 TET2 (0.40) TET2TET3TET1GRIK1GRIK2
SCHEMBL1552251 0.72 TET2 (0.40) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1108761-A2 Polymer film, and polymeric compound for the production thereof CANON KABUSHIKI KAISHA (JP) 2001-06-20 EP disclosed