SCHEMBL2180876

SCHEMBL2180876

C=C(CC(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.43
TET3 O43151 1/20 0.43
TET1 Q8NFU7 1/20 0.43
GRIK1 P39086 1/20 0.42
GRIK2 Q13002 1/20 0.42
GRM1 Q13255 1/20 0.42
GRM2 Q14416 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14125809 0.88 TET2 (0.41) TET2TET3TET1GRIK1GRIK2
SCHEMBL7768142 0.85 TET2 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL6061456 0.85 TET2 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL10938859 0.81 TET2 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL1704335 0.78 SLC22A6 (0.38)
SCHEMBL2966907 0.72
SCHEMBL261730 0.71 TET2 (0.48) TET2TET3TET1GRIK1GRIK2
SCHEMBL2001779 0.69 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
SCHEMBL6064308 0.69 TET2 (0.50) TET2TET3TET1GRIK1GRIK2
SCHEMBL1995655 0.69 TET2 (0.56) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9599758-B2 Optical reflective film and optical reflector using the same Konica Minolta, Inc. (JP) 2017-03-21 US disclosed
US-20150285974-A1 OPTICAL REFLECTIVE FILM AND OPTICAL REFLECTOR USING THE SAME Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-20120315478-A1 PLASTIC OPTICAL FIBER Naritomi, Masaki (JP) 2012-12-13 US disclosed
WO-2011080896-A1 PLASTIC OPTICAL FIBER NARITOMI MASAKI (JP) 2011-07-07 WO disclosed