Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693854 | 0.86 | TRPV4 (0.41) | TRPV4KHKCYP11B2ALDH1A1MAPK1 | |
| SCHEMBL16122585 | 0.85 | ALDH1A1 (0.36) | TRPV4KHKCYP11B2ARALDH1A1 | |
| SCHEMBL7771115 | 0.84 | TRPV4 (0.42) | TRPV4KHK | |
| SCHEMBL8045190 | 0.83 | ALDH1A1 (0.37) | TRPV4KHKCYP11B2ARALDH1A1 | |
| SCHEMBL8049906 | 0.83 | TRPV4 (0.41) | TRPV4KHKCYP11B2ARALDH1A1 | |
| SCHEMBL8664249 | 0.82 | TRPV4 (0.39) | TRPV4KHKCYP11B2ARALDH1A1 | |
| SCHEMBL8727200 | 0.80 | TRPV4 (0.38) | TRPV4KHKCYP11B2ARALDH1A1 | |
| SCHEMBL7649737 | 0.77 | TRPV4 (0.45) | TRPV4KHKCYP11B2ALDH1A1CYP11B1 | |
| SCHEMBL5338291 | 0.77 | TRPV4 (0.45) | TRPV4KHKCYP11B2ALDH1A1CYP11B1 | |
| SCHEMBL7043988 | 0.77 | KHK (0.43) | TRPV4KHKCYP11B2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2169542-A | — | — | None | — | — | JP | disclosed |
| EP-0748850-B1 | Dyestuffs, process for their preparation and their use | CIBA SC HOLDING AG (CH) | 2001-07-04 | — | — | EP | disclosed |
| EP-0735113-B1 | Mixtures of reactive dyes and their use | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| EP-0735107-B1 | Reactive dyes and their use | CIBA SC HOLDING AG (CH) | 2000-08-30 | — | — | EP | disclosed |
| EP-0625551-B1 | Mixtures of dyes, process for their preparation and the use thereof | CIBA GEIGY AG (CH) | 1999-09-29 | — | — | EP | disclosed |
| EP-0631008-B1 | Process for the washing of printings or dyeings on cellulose containing textile materials | CIBA GEIGY AG (CH) | 1999-08-18 | — | — | EP | disclosed |
| US-5931975-A | TRIAZINE REACTIVE DYES | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |
| US-5892006-A | CONTAINING S-TRIAZINE RINGS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0625549-B1 | Reactive dyes, process for their preparation and the use thereof | CIBA GEIGY AG (CH) | 1998-07-01 | — | — | EP | disclosed |
| US-5735911-A | TRIAZINE DYES HAVING GOOD WET AND LIGHT FASTNESS PROPERTIES | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-04-07 | — | — | US | disclosed |
| EP-0097289-B1 | AZO DYESTUFFS | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |
| EP-0190615-A2 | Reactive dyes | BAYER AG (DE) | 1986-08-13 | — | — | EP | disclosed |
| EP-0177978-A2 | Naphthol amine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | disclosed |
| EP-0158882-A2 | Triphenedioxazine dyes | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0128316-A1 | Reactive disazo dyes | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0050266-B1 | REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS THAT CONTAIN HYDROXYL AND/OR NITROGEN | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |
| EP-0043411-B1 | REACTIVE DISAZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS CONTAINING NITROGEN AND/OR HYDROXYLE GROUPS | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0097289-A2 | Azo dyestuffs | BAYER AG (DE) | 1984-01-04 | — | — | EP | disclosed |
| EP-0050266-A1 | Reactive disazo dyes, process for their preparation and their use in dyeing and printing materials that contain hydroxyl and/or nitrogen | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0043411-A2 | Reactive disazo dyestuffs, process for their preparation and their use in dyeing and printing materials containing nitrogen and/or hydroxyle groups | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |