Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979412 | 0.80 | KMT2A (0.60) | KMT2AMEN1PGRGRM4GRM1 | |
| SCHEMBL3819605 | 0.76 | MEN1 (0.51) | KMT2AMEN1PGRGRM4GRM1 | |
| SCHEMBL19365875 | 0.74 | NR1H2 (0.69) | KMT2AMEN1PGRGRM4GRM1 | |
| SCHEMBL9001025 | 0.71 | MEN1 (0.57) | KMT2AMEN1NR1H2ALDH1A1GAA | |
| SCHEMBL11022012 | 0.71 | DPP4 (0.68) | KMT2AMEN1PGRGRM4GRM1 | |
| SCHEMBL9009727 | 0.70 | GRM1 (0.32) | GRM4GRM1GRM7ANPEPDPP4 | |
| SCHEMBL1500541 | 0.70 | HSPA1A (0.67) | KMT2AMEN1PGRGRM4GRM1 | |
| SCHEMBL1735119 | 0.69 | MEN1 (0.58) | KMT2AMEN1GRM4GRM1USP2 | |
| SCHEMBL2892154 | 0.69 | KMT2A (0.47) | KMT2AMEN1PGRGRM4GRM1 | |
| SCHEMBL11131721 | 0.68 | TAAR1 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| EP-0740690-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995020014-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |