Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL7764537 | 0.93 | GPR84 (0.44) | GPR84FFAR1S1PR2S1PR1S1PR4 | |
| Acetic Acid SCHEMBL7764900 | 0.91 | THRA (0.42) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Lactic Acid SCHEMBL7768064 | 0.89 | CSNK1E (0.41) | GPR84FFAR1ACE2 | |
| Succinic Acid SCHEMBL7768273 | 0.88 | S1PR1 (0.48) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Malonic Acid SCHEMBL7765984 | 0.88 | S1PR1 (0.43) | GPR84S1PR2S1PR1S1PR4S1PR3 | |
| Adipic Acid SCHEMBL7764425 | 0.87 | FFAR4 (0.51) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL7764492 | 0.86 | THRA (0.37) | MAPTTHRATHRBLCK | |
| Hydrochloric Acid SCHEMBL7760906 | 0.86 | THRA (0.37) | MAPTTHRATHRBLCK | |
| Hydrochloric Acid SCHEMBL8720967 | 0.86 | THRA (0.37) | MAPTTHRATHRBLCK | |
| Hydrochloric Acid SCHEMBL8719708 | 0.86 | THRA (0.37) | MAPTTHRATHRBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |