Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 9/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768373 | 0.90 | ADRB1 (0.44) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7768358 | 0.88 | ADRB1 (0.44) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6319575 | 0.81 | ADRB1 (0.48) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6319580 | 0.81 | ADRB1 (0.48) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6322699 | 0.80 | MAPT (0.62) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6322703 | 0.80 | MAPT (0.62) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7769288 | 0.79 | KMT2A (0.48) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6322165 | 0.79 | SMN1; SMN2 (0.46) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6322166 | 0.79 | SMN1; SMN2 (0.46) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7597017 | 0.79 | MEN1 (0.53) | ADRB1ADRB3MEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |