Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 11/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768357 | 0.88 | ADRB1 (0.44) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7768373 | 0.84 | ADRB1 (0.44) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6322703 | 0.81 | MAPT (0.62) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6322699 | 0.81 | MAPT (0.62) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7769288 | 0.80 | KMT2A (0.48) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6323867 | 0.80 | POLB (0.43) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL6323870 | 0.80 | POLB (0.43) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6319138 | 0.78 | MAPT (0.51) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6319148 | 0.78 | MAPT (0.51) | ADRB1ADRB3MEN1KMT2AALDH1A1 | |
| SCHEMBL7770274 | 0.78 | ALDH1A1 (0.47) | ADRB1ADRB3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |