Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 7/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362633 | 0.74 | SLC6A1 (0.45) | SLC6A1PTGS1PDE4A | |
| SCHEMBL14301505 | 0.73 | SLC6A1 (0.72) | SLC6A1PTGS1PDE4A | |
| SCHEMBL14021177 | 0.73 | SLC6A1 (0.72) | SLC6A1PTGS1PDE4A | |
| SCHEMBL7362815 | 0.70 | SLC6A1 (0.63) | SLC6A1PTGS1PDE4A | |
| SCHEMBL5278238 | 0.69 | SLC6A1 (0.73) | SLC6A1PTGS1PDE4A | |
| SCHEMBL7929356 | 0.69 | SLC6A1 (0.61) | SLC6A1PTGS1PDE4A | |
| Tiagabine SCHEMBL34653 | 0.69 | SLC6A1 (1.00) | SLC6A1PTGS1PDE4A | |
| Tiagabine SCHEMBL342814 | 0.69 | SLC6A1 (1.00) | SLC6A1PTGS1PDE4A | |
| SCHEMBL12163145 | 0.69 | SLC6A1 (0.67) | SLC6A1PTGS1PDE4A | |
| Tiagabine SCHEMBL3272861 | 0.69 | SLC6A1 (1.00) | SLC6A1PTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109783-A2 | GABA UPTAKE INHIBITORS HAVING A PYRROLIDINE STRUCTURE | BDD Berolina Drug Development AB (SE) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014064-A2 | GABA UPTAKE INHIBITORS HAVING A PYRROLIDINE STRUCTURE | BDD BEROLINA DRUG DEVELOPMENT AB (SE) | 2000-03-16 | — | — | WO | disclosed |