Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 5/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524274 | 0.86 | TBXAS1 (0.40) | SLC6A1PTGS1PDE4A | |
| SCHEMBL9773503 | 0.86 | TBXAS1 (0.40) | SLC6A1PTGS1PDE4A | |
| SCHEMBL9524272 | 0.86 | TBXAS1 (0.40) | SLC6A1PTGS1PDE4A | |
| SCHEMBL9773499 | 0.86 | TBXAS1 (0.40) | SLC6A1PTGS1PDE4A | |
| SCHEMBL10407492 | 0.84 | SLC6A1 (0.36) | SLC6A1PTGS1PDE4A | |
| SCHEMBL10407493 | 0.84 | SLC6A1 (0.36) | SLC6A1PTGS1PDE4A | |
| SCHEMBL3276106 | 0.79 | GSK3B (0.47) | SLC6A1PTGS1PDE4A | |
| SCHEMBL7768683 | 0.79 | GSK3B (0.47) | SLC6A1PTGS1PDE4A | |
| SCHEMBL27950483 | 0.74 | TBXAS1 (0.48) | SLC6A1PTGS1PDE4A | |
| SCHEMBL7768658 | 0.74 | SLC6A1 (0.53) | SLC6A1PTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570703-B | The preparation and purification method of Tiagabine Hydrochloride | ZHAO XUEQING (CN) | 2016-03-23 | — | — | CN | disclosed |
| US-9290486-B1 | Compositions and methods for the treatment of epilepsy | CELLIX BIO PRIVATE LIMITED (IN) | 2016-03-22 | — | — | US | disclosed |
| US-9290486-B1 | Compositions and methods for the treatment of epilepsy | CELLIX BIO PRIVATE LIMITED (IN) | 2016-03-22 | — | — | US | disclosed |
| CN-103570703-A | Preparation and purifying method of tiagabine hydrochloride | ZHAO XUEQING | 2014-02-12 | — | — | CN | disclosed |
| EP-1109783-A2 | GABA UPTAKE INHIBITORS HAVING A PYRROLIDINE STRUCTURE | BDD Berolina Drug Development AB (SE) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014064-A2 | GABA UPTAKE INHIBITORS HAVING A PYRROLIDINE STRUCTURE | BDD BEROLINA DRUG DEVELOPMENT AB (SE) | 2000-03-16 | — | — | WO | disclosed |
| EP-0236342-B1 | AMINO ACID DERIVATIVES | NOVO NORDISK A/S (DK) | 1991-09-11 | — | — | EP | disclosed |
| US-5010090-A | N-(butenyl substituted) azaheterocyclic carboxylic acids | NOVO NORDISK A/S. (DK) | 1991-04-23 | — | — | US | disclosed |
| EP-0236342-A1 | AMINO ACID DERIVATIVES. | NOVO INDUSTRI AS (DK) | 1987-09-16 | — | — | EP | disclosed |
| WO-1987000171-A1 | AMINO ACID DERIVATIVES | NOVO INDUSTRI A/S (DK) | 1987-01-15 | — | — | WO | disclosed |