Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768194 | 0.84 | — | — | |
| SCHEMBL8421996 | 0.78 | DRD2 (0.36) | TSHRMEN1HTTKMT2A | |
| SCHEMBL7766973 | 0.69 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL27541059 | 0.68 | DPP4 (0.37) | DPP4MEN1KMT2A | |
| SCHEMBL7768193 | 0.68 | SMN1; SMN2 (0.34) | DPP4 | |
| SCHEMBL28025455 | 0.67 | DPP4 (0.39) | DPP4 | |
| SCHEMBL29143876 | 0.66 | EPHX2 (0.43) | DPP4TSHRMEN1KMT2A | |
| SCHEMBL8421947 | 0.65 | TP53 (0.31) | — | |
| SCHEMBL13886100 | 0.62 | POLB (0.50) | DPP4 | |
| SCHEMBL2757948 | 0.62 | POLB (0.50) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0744401-B1 | Process for the preparation of optically active 2-piperazine carboxylic acid derivatives | LONZA AG (CH) | 2001-11-21 | — | — | EP | disclosed |
| EP-1125930-A1 | Optically active piperazine-2-carboxylic acid derivatives and process for their preparation | LONZA AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| EP-0744401-A2 | Process of preparation of optically active 2-piperazine carboxylic acid | LONZA AG (CH) | 1996-11-27 | — | — | EP | disclosed |