Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768121 | 0.76 | USP2 (0.37) | SMN1; SMN2 | |
| SCHEMBL8418703 | 0.75 | ADRA1D (0.40) | — | |
| SCHEMBL28084531 | 0.72 | L3MBTL1 (0.37) | SMN1; SMN2 | |
| Acetic Acid SCHEMBL8418146 | 0.72 | ADRA1D (0.39) | — | |
| SCHEMBL27541059 | 0.72 | DPP4 (0.37) | SMN1; SMN2 | |
| SCHEMBL7582689 | 0.71 | L3MBTL1 (0.33) | — | |
| SCHEMBL7768194 | 0.69 | — | — | |
| SCHEMBL7768684 | 0.69 | DPP4 (0.34) | — | |
| SCHEMBL17621809 | 0.67 | ITGB2 (0.33) | — | |
| SCHEMBL28044432 | 0.67 | HRH3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0744401-B1 | Process for the preparation of optically active 2-piperazine carboxylic acid derivatives | LONZA AG (CH) | 2001-11-21 | — | — | EP | disclosed |
| EP-1125930-A1 | Optically active piperazine-2-carboxylic acid derivatives and process for their preparation | LONZA AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| EP-0744401-A2 | Process of preparation of optically active 2-piperazine carboxylic acid | LONZA AG (CH) | 1996-11-27 | — | — | EP | disclosed |