Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768792 | 1.00 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL7772686 | 0.92 | CYSLTR1 (0.43) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL7772692 | 0.92 | CYSLTR1 (0.43) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL7772774 | 0.84 | LMNA (0.52) | LMNASMN1; SMN2MEN1NR1I2CHRM2 | |
| SCHEMBL7772770 | 0.84 | LMNA (0.52) | LMNASMN1; SMN2MEN1NR1I2CHRM2 | |
| SCHEMBL10442994 | 0.83 | SGMS2 (0.52) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL5046787 | 0.83 | SGMS2 (0.52) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL5046789 | 0.83 | SGMS2 (0.52) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL2446724 | 0.78 | ALDH1A1 (0.65) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL3102228 | 0.76 | CA12 (0.56) | SMN1; SMN2GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122238-A1 | METHYL ACETATE DERIVATIVES AND PESTICIDE COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |