Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.86 |
| ▸ | HTR2A | P28223 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783785 | 0.92 | APLNR (1.00) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL18256578 | 0.91 | APLNR (0.77) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL29580030 | 0.90 | APLNR (0.75) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL31114343 | 0.90 | APLNR (0.75) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL14971128 | 0.90 | APLNR (0.75) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL7002432 | 0.89 | APLNR (0.73) | APLNRHTR2AHTR2CHDAC3HDAC1 | |
| SCHEMBL12522890 | 0.87 | APLNR (0.83) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL2883792 | 0.87 | APLNR (0.71) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL17138360 | 0.87 | APLNR (0.71) | APLNRHTR2AHTR2CTSHR | |
| SCHEMBL31579985 | 0.87 | APLNR (0.71) | APLNRHTR2AHTR2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3007732-B1 | BIFUNCTIONAL CHELATING AGENTS BASED ON THE 1,4-DIAZEPINE SCAFFOLD (DAZA) FOR NON-INVASIVE MOLECULAR IMAGING | UNIV MAINZ JOHANNES GUTENBERG (DE) | 2018-09-26 | — | — | EP | disclosed |
| US-20160136309-A1 | BIFUNCTIONAL CHELATING AGENTS BASED ON THE 1,4-DIAZEPINE SCAFFOLD (DAZA) FOR NON-INVASIVE MOLECULAR IMAGING | SPECIALCHEMICALS VERTRIEB GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| EP-3007732-A2 | BIFUNCTIONAL CHELATING AGENTS BASED ON THE 1,4-DIAZEPINE SCAFFOLD (DAZA) FOR NON-INVASIVE MOLECULAR IMAGING | Johannes-Gutenberg-Universität Mainz (DE) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014198478-A2 | BIFUNCTIONAL CHELATING AGENTS BASED ON THE 1,4-DIAZEPINE SCAFFOLD (DAZA) FOR NON-INVASIVE MOLECULAR IMAGING | Johannes Gutenberg-Universität Mainz (DE) | 2014-12-18 | — | — | WO | disclosed |
| EP-0781552-B1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-6011069-A | N-POLYISOPRENYL-N,N'-DIBENZYLETHYLENEDIAMINES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0781552-A1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160136309-A1 | BIFUNCTIONAL CHELATING AGENTS BASED ON THE 1,4-DIAZEPINE SCAFFOLD (DAZA) FOR NON-INVASIVE MOLECULAR IMAGING | DAZAP1, BAZ2A, BAZ1A | APLNR 1283/4885HTR2A 757/4885HTR2C 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.