SCHEMBL783785

SCHEMBL783785

COc1ccc(CNCc2ccc(OC)cc2OC)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 1.00
HTR2A P28223 2/20 0.63
HTR2C P28335 2/20 0.63
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HDAC3 O15379 1/20 0.57
HDAC1 Q13547 1/20 0.57
HDAC2 Q92769 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 1/20 0.56
TSHR P16473 2/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27163106 0.93 APLNR (0.86) APLNRHTR2AHTR2CMEN1KMT2A
SCHEMBL7768853 0.92 APLNR (0.86) APLNRHTR2AHTR2CMEN1KMT2A
SCHEMBL21159301 0.91 APLNR (0.83) APLNRMEN1KMT2AKDM4EALDH1A1
SCHEMBL12522890 0.91 APLNR (0.83) APLNRHTR2AHTR2CMEN1KMT2A
SCHEMBL28318209 0.89 APLNR (0.80) APLNRHTR2AHTR2CMEN1KMT2A
SCHEMBL6099643 0.89 APLNR (0.80) APLNRHTR2AHTR2CMEN1KMT2A
SCHEMBL8880359 0.88 APLNR (0.78) APLNRHTR2AHTR2CMEN1KMT2A
SCHEMBL18256578 0.88 APLNR (0.77) APLNRHTR2AHTR2CMEN1KMT2A
Hydrochloric Acid SCHEMBL11092397 0.87 APLNR (0.76) APLNRHTR2AHTR2CMEN1KMT2A
SCHEMBL680457 0.86 APLNR (0.76) APLNRHTR2AHTR2CMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409556-B Preparation method of 3, 4-disubstituted-2-aminobenzaldehyde 兰州康鹏威耳化工有限公司 2024-10-18 CN claimed
CN-116706230-B High-voltage electrolyte for lithium battery 浙江大学 2024-02-02 CN claimed
CN-116706230-A High-voltage electrolyte for lithium battery 浙江大学 2023-09-05 CN claimed
CN-114409556-A Preparation method of 3, 4-disubstituted-2-aminobenzaldehyde 兰州康鹏威耳化工有限公司 2022-04-29 CN claimed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
EP-4744661-A2 NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2026-05-20 EP disclosed
US-12624011-B2 Oxadiazole derivative Sumitomo Pharma Co., Ltd. (JP) 2026-05-12 US disclosed
EP-4076459-B1 PRMT5 INHIBITORS MERCK SHARP & DOHME LLC (US) 2026-04-29 EP disclosed
EP-4731306-A1 CYSTOBACTAMID DERIVATIVES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2026-04-29 EP disclosed
US-12595248-B2 PRMT5 inhibitors MERCK SHARP & DOHME LLC (US) 2026-04-07 US disclosed
EP-4716685-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2026-04-01 EP disclosed
US-12590096-B2 Imidazo[2,1-f][1,2,4]triazin-4-amine as TLR8 agonists BeOne Medicines | GmbH (CH) 2026-03-31 US disclosed
EP-1685119-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS Abbott Laboratories (US) 2006-08-02 EP disclosed
US-20060128706-A1 Apoptosis promoters ABBVIE INC. 2006-06-15 US disclosed
US-20050159427-A1 N-acylsulfonamide apoptosis promoters ABBOTT LABORATORIES 2005-07-21 US disclosed
WO-2005049593-A2 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ABBOTT LABORATORIES (US) 2005-06-02 WO disclosed
WO-2005049594-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ABBOTT LABORATORIES (US) 2005-06-02 WO disclosed
WO-2002018031-A2 A DEVICE AND METHOD FOR REMOVING PARTICULATE MATERIAL FROM SUSPENSIONS ABBOTT LABORATORIES (US) 2002-03-07 WO disclosed
US-6143917-A FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD UBE INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128706-A1 Apoptosis promoters BAX, BCL2, API5 APLNR 1947/4885HTR2A 3715/4885HTR2C 4428/4885
US-12595248-B2 PRMT5 inhibitors PRMT5, PRMT1, PRMT6 APLNR 4079/4885HTR2A 3582/4885HTR2C 1891/4885
US-20050159427-A1 N-acylsulfonamide apoptosis promoters BAX, API5, CCAR2 APLNR 1033/4885HTR2A 4096/4885HTR2C 4529/4885
US-12624011-B2 Oxadiazole derivative HSD3B1, CBR3, CBR1 APLNR 4811/4885HTR2A 1896/4885HTR2C 837/4885
US-12590096-B2 Imidazo[2,1-f][1,2,4]triazin-4-amine as TLR8 agonists TLR8, TLR7, TLR1 APLNR 80/4885HTR2A 337/4885HTR2C 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.