Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | JUN | P05412 | 1/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833247 | 0.93 | TAAR1 (0.62) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL19326714 | 0.92 | KDM4E (0.63) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL11856117 | 0.92 | FOS (0.57) | FOSTTRJUNNR3C1HSD17B1 | |
| Hydrochloric Acid SCHEMBL16799316 | 0.90 | KDM4E (0.61) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL29442241 | 0.90 | KDM4E (0.61) | KDM4EPOLB | |
| SCHEMBL906529 | 0.89 | KDM4E (0.60) | KDM4EPOLBCYP3A4ALOX15ALDH1A1 | |
| SCHEMBL11856806 | 0.88 | TAAR1 (0.57) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL1042189 | 0.88 | ALDH1A1 (0.62) | CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL9416518 | 0.86 | TSHR (0.58) | FOSTTRJUNNR3C1HSD17B1 | |
| Hydrochloric Acid SCHEMBL16799320 | 0.86 | TAAR1 (0.58) | FOSTTRJUNNR3C1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781552-B1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-6011069-A | N-POLYISOPRENYL-N,N'-DIBENZYLETHYLENEDIAMINES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0781552-A1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |