Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042189 | 0.95 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2800439 | 0.94 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL598034 | 0.94 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22788513 | 0.94 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11856117 | 0.91 | FOS (0.57) | — | |
| SCHEMBL29442241 | 0.89 | KDM4E (0.61) | KDM4EPOLB | |
| SCHEMBL7768865 | 0.89 | FOS (0.62) | KDM4EPOLBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5537900 | 0.87 | TRPV1 (0.69) | ALDH1A1CYP1A2CYP3A4CYP2D6HPGD | |
| SCHEMBL5351451 | 0.87 | TRPV1 (0.69) | ALDH1A1CYP1A2CYP3A4CYP2D6HPGD | |
| SCHEMBL29207410 | 0.86 | TRPV1 (0.69) | ALDH1A1CYP1A2CYP3A4CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276356-B1 | WARMING SENSATE COMPOSITION | FIRMENICH & CIE (CH) | 2013-06-19 | — | — | EP | claimed |
| EP-2276356-A1 | WARMING SENSATE COMPOSITION | Firmenich S.A. (CH) | 2011-01-26 | — | — | EP | claimed |
| US-20110015227-A1 | WARMING SENSATE COMPOSITION | FIRMENICH SA (CH) | 2011-01-20 | — | — | US | claimed |
| WO-2009127992-A1 | WARMING SENSATE COMPOSITION | FIRMENICH SA (CH) | 2009-10-22 | — | — | WO | claimed |
| EP-1874132-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2008-01-09 | — | — | EP | claimed |
| US-20080000614-A1 | HOT FLAVOR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2008-01-03 | — | — | US | claimed |
| WO-2006109241-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2006-10-19 | — | — | WO | claimed |
| WO-2012175276-A1 | TASTE MODIFYING COMPOUND INCLUDING EVODIAMINE | FIRMENICH SA (CH) | 2012-12-27 | — | — | WO | disclosed |
| EP-1874132-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2008-01-09 | — | — | EP | disclosed |
| US-20080000614-A1 | HOT FLAVOR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2008-01-03 | — | — | US | disclosed |
| WO-2006109241-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2006-10-19 | — | — | WO | disclosed |
| CN-1411360-A | Method of treating skin conditions | AVON PROD INC (US) | 2003-04-16 | — | — | CN | disclosed |
| US-3983151-A | Process for the preparation of 4-hydroxy-3-methoxy-phenylacetonitrile | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015227-A1 | WARMING SENSATE COMPOSITION | TAS1R3, TAS2R30, TAS2R50 | KDM4E 4523/4885POLB 3827/4885ALDH1A1 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.