Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12615992 | 0.85 | ALDH1A1 (0.68) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL5549180 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL5330184 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL30084182 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL14242848 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL8109135 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL436604 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL8540440 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL28955008 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL20237265 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788487-B1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | NOVARTIS AG (CH) | 2001-07-25 | — | — | EP | disclosed |
| EP-0788487-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | Novartis AG (CH) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013489-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | NOVARTIS AG (CH) | 1996-05-09 | — | — | WO | disclosed |