Phenothiazine

Phenothiazine

SCHEMBL7768973

Oc1ccc(O)cc1.c1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.77
MAPT P10636 8/20 0.77
GAA P10253 7/20 0.77
MEN1 O00255 4/20 0.77
KMT2A Q03164 4/20 0.77
SNCA P37840 3/20 0.77
BCHE P06276 2/20 0.77
ACHE P22303 2/20 0.77
ALOX15 P16050 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
CYP1A2 P05177 1/20 0.77
POLB P06746 1/20 0.77
CYP3A4 P08684 1/20 0.77
ADORA3 P0DMS8 1/20 0.77
ALOX12 P18054 1/20 0.77
MAOA P21397 1/20 0.77
CNR1 P21554 1/20 0.77
PTGS1 P23219 1/20 0.77
SLC6A2 P23975 1/20 0.77
HTR2C P28335 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL27756460 0.98 NOX1 (0.74) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL22584033 0.93 NOX1 (0.74) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL29352248 0.88 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL2504207 0.88 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL29349533 0.88 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL9114 0.88 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL6315328 0.88 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
SCHEMBL299552 0.88 NOX1 (0.65) NOX1MAPTGAAMEN1KMT2A
SCHEMBL2720811 0.88 NOX1 (0.65) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL6025548 0.86 NOX1 (0.77) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480333-A Comprehensive polycarboxylic acid water reducing agent and preparation method and application thereof 河南城建学院 2021-03-12 CN claimed
CN-109627396-B Preparation method of ether ester copolymerization type polycarboxylate superplasticizer with improved rheological property 科之杰新材料集团有限公司 2021-12-07 CN disclosed
CN-112480333-A Comprehensive polycarboxylic acid water reducing agent and preparation method and application thereof 河南城建学院 2021-03-12 CN disclosed
CN-106588647-B Method for preventing polymerization reaction in methyl methacrylate preparation process 中国石油集团东北炼化工程有限公司吉林设计院 2020-04-17 CN disclosed
CN-106588647-A Method for preventing polymerization in methyl methacrylate preparation process 中国石油集团东北炼化工程有限公司吉林设计院 2017-04-26 CN disclosed
US-6210536-B1 DISTILLATION OF ACRYLIC OR METHACRYLIC ACID OR ESTER IN PRESENCE OF POLYMERIZATION INHIBITOR COMPRISING N,N*-DINITROSO PHENYLENEDIAMINE COMPOUND, A HYDROQUINONE OR HYDROQUINONE MONOMETHYL ETHER, PHENYLENEDIAMINE COMPOUND, PHENOTHIAZINE UNIROYAL CHEMICAL COMPANY, INC. 2001-04-03 US disclosed
US-5262450-A Pentaerythritol triacrylate, cyclohexanedimethanol divinyl ether ISP INVESTMENTS INC. (US) 1993-11-16 US disclosed
EP-0522709-A2 Polymerization inhibitors for acrylic acids and esters UNIROYAL CHEMICAL COMPANY, Inc. (US) 1993-01-13 EP disclosed
WO-1992012186-A1 ABRASION AND WATER-RESISTANT RADIATION CURABLE COATINGS ISP INVESTMENTS INC. (US) 1992-07-23 WO disclosed
EP-0029105-B1 RADIATION CURABLE COATING COMPOSITION, PROCESS FOR COATING A SUBSTRATE THEREWITH, EYEGLASSES AND LAMINATE GAF CORPORATION (US) 1986-02-05 EP disclosed
US-4319811-A OF TRIACRYLATES AND N-BINYL IMIDO GROUP GAF CORPORATION (US) 1982-03-16 US disclosed
EP-0029105-A2 Radiation curable coating composition, process for coating a substrate therewith, eyeglasses and laminate GAF CORPORATION (US) 1981-05-27 EP disclosed